Description: Polymyxin B2, a significant component of polymyxin B, is an antibiotic cationic lipopeptide initially derived from B. polymyxa. This compound effectively inhibits P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloacae strains, exhibiting minimum inhibitory concentrations (MICs) of 1-2, 0.5-1,...

Polymyxin B2 is an antibiotic and a major constituent of the cationic lipopeptide antibiotic polymyxin B (Cay-14157) originally isolated from B. polymyxa. It is active against P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloacae strains (MICs = 1-2, 0.5-1, 0.25-0.5, and 0.25-1 µg/ml, respectively). In vivo,...