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Item number: Cay17177-10

p-iodo-Clonidine is a partial agonist of the alpha2-adrenergic receptor, minimally inhibiting adenylate cyclase through this Gi protein-coupled receptor although it binds avidly (Ki = 1.0 nM). It potentiates platelet aggregation by ADP (EC50 = 1.5 µM) and inhibits epinephrine-induced aggregation (IC50 = 5.1...

Keywords:	N-(2,6-dichloro-4-iodophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride
Application:	alpha2-adrenergic receptor agonist
CAS	108294-57-1
MW:	392.5 D

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