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Item number: TGM-T5359-100mg

Description: RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair. Target: Interleukin. Smiles: Brc1ccc(Nc2nc(cs2)-c2ccccc2)cc1. References: Shkhyan R, et al. Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair....

Application:	gp130 modulator
CAS	108237-91-8
MW:	331.23 D

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RCGD 423

Item number: Cay31420-1

RCGD 423 is a modulator of gp130. It increases levels of phosphorylated STAT3 and Myc in isolated pig articular chondrocytes (EC50s = 4.5-7.2 µM), effects that can be reversed by the gp130 inhibitor SC144 (Cay-29714). RCGD 423 reduces cellular apoptosis and hypertrophy induced by bone morphogenic protein 4 (BMP4) in...

Keywords:	N-(4-bromophenyl)-4-phenyl-2-thiazolamine
Application:	gp130 modulator
CAS	108237-91-8
MW:	331.2 D

From 49.00€ *

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