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Zamicastat
Item number: Cay42101-1
Zamicastat is an inhibitor of dopamine beta-hydroxylase (DbetaH). It increases levels of norepinephrine and decreases levels of dopamine in the hearts of aged spontaneously hypertensive rats (SHRs) when administered at a dose of 30 mg/kg per day. Zamicastat decreases diastolic and systolic blood pressure in the same...
| Keywords: | BIA 5-1058,... |
| Application: | DbetaH inhibitor |
| CAS | 1080028-80-3 |
| MW: | 401.47 D |
From 91.00€
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Zamicastat
Item number: TGM-T13383-100mg
Description: Zamicastat (BIA 5-1058) is an inhibitor of dopamine beta-hydroxylase (DBH) and a concentration-dependent dual inhibitor of P-gp and BCRP, with IC50 values of 73.8 µM and 17.0 µM, respectively. Target: P-gp, BCRP, Hydroxylase. Smiles: Fc1cc(F)c2OC[C@@H](Cc2c1)n1c(CCNCc2ccccc2)c[nH]c1=S. References:...
| Keywords: | BIA 5-1058 |
| CAS | 1080028-80-3 |
| MW: | 401.47 D |
From 83.00€
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