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Item number: Cay35326-1

CAY10790 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 2.8 µM) and G protein-coupled bile acid receptor 1 (GPBAR1) agonist. It induces receptor transactivation in HEK293T cells expressing human GPBAR1 (EC50 = 3 µM). CAY10790 (10 µM) reduces TNF-alpha and IL-1beta levels in LPS-stimulated RAW...

Keywords:	3-(2-quinolinylmethoxy)-benzoic acid
Application:	CysLT1 receptor antagonist, GPBAR1 agonist
CAS	107813-86-5
MW:	279.3 D

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