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Plecanatide (acetate)
Item number: Cay33878-1
Plecanatide is a peptide agonist of the guanylate cyclase C receptor. It stimulates cGMP production in T84 colon cancer cells (EC50 = 170 nM). Plecanatide (10 ppm in the diet) reduces increases in the number of neoplastic colon epithelial cells expressing Ki-67, a marker of cell proliferation, induced by dextran...
| Keywords: | SP-304,... |
| Application: | GUCY2C peptide agonist |
| CAS | 1075732-84-1 |
| MW: | 1741.9 D |
From 97.00€
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Plecanatide acetate
Item number: TGM-T12501-10mg
Description: Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis. Target: Others. Smiles:...
| Application: | GUCY2C peptide agonist |
| CAS | 1075732-84-1 |
| MW: | 1741.94 D |
From 210.00€
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