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Item number: Cay33878-1

Plecanatide is a peptide agonist of the guanylate cyclase C receptor. It stimulates cGMP production in T84 colon cancer cells (EC50 = 170 nM). Plecanatide (10 ppm in the diet) reduces increases in the number of neoplastic colon epithelial cells expressing Ki-67, a marker of cell proliferation, induced by dextran...

Keywords:	SP-304,...
Application:	GUCY2C peptide agonist
CAS	1075732-84-1
MW:	1741.9 D

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