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ABL 127
Item number: Cay10833-1
ABL 127 is a covalent aza-beta-lactam inhibitor of protein phosphatase methylesterase-1 (PME-1, IC50 = 4.2 nM). It selectively inhibits PME-1 over 50 other serine hydrolases in MDA-MB-231 and HEK293T cell lysates at 10 µM. ABL 127 decreases proliferation of Ishikawa cells and migration of ECC-1 endometrial carcinoma...
| Keywords: | (3R)-3-cyclopentyl-4-oxo-3-phenyl-1,2-diazetidine-1,2-dicarboxylic acid, 1,2-dimethyl ester |
| Application: | Protein phosphatase methylesterase-1 inhibitor |
| CAS | 1073529-41-5 |
| MW: | 332.4 D |
From 58.00€
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ABL127
Item number: TGM-T14084-1mg
Description: ABL127 is a selective and covalent inhibitor of protein methylesterase 1 (PME-1), with IC50 values of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively. Target: Others. Smiles: COC(=O)N1N(C(=O)OC)[C@@](C2CCCC2)(C1=O)C1=CC=CC=C1. References: Pusey M, et al. Inhibition of protein...
| Application: | Protein phosphatase methylesterase-1 inhibitor |
| CAS | 1073529-41-5 |
| MW: | 332.35 D |
From 125.00€
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