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ABL 127
ABL 127

Item number: Cay10833-1

ABL 127 is a covalent aza-beta-lactam inhibitor of protein phosphatase methylesterase-1 (PME-1, IC50 = 4.2 nM). It selectively inhibits PME-1 over 50 other serine hydrolases in MDA-MB-231 and HEK293T cell lysates at 10 µM. ABL 127 decreases proliferation of Ishikawa cells and migration of ECC-1 endometrial carcinoma...
Keywords: (3R)-3-cyclopentyl-4-oxo-3-phenyl-1,2-diazetidine-1,2-dicarboxylic acid, 1,2-dimethyl ester
Application: Protein phosphatase methylesterase-1 inhibitor
CAS 1073529-41-5
MW: 332.4 D
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