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Defactinib
Item number: Cay17737-1
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that plays a vital role in many oncogenic pathways. Defactinib is a dose-dependent inhibitor of FAK, with maximal inhibition of FAK autophosphorylation in cells achieved at 10 µM. It is less effective against the related kinase PYK2. Defactinib restores...
| Keywords: | PF-04554878, VS-6063,... |
| Application: | FAK inhibitor |
| CAS | 1073154-85-4 |
| MW: | 510.5 D |
From 56.00€
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Defactinib
Item number: LKT-D1722.100
FAK inhibitor.
| Keywords: | VS-6063, PF-04554878 |
| Application: | FAK inhibitor |
| CAS | 1073154-85-4 |
| MW: | 510.49 D |
From 151.00€
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Defactinib
Item number: TGM-T1996-10mg
Description: Defactinib (VS-6063) is a second-generation inhibitor of FAK that inhibits FAK phosphorylation at the Tyr397 site. Defactinib has potential antitumor activity. Target: FAK. Smiles: CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1
| Keywords: | PF-04554878 , VS-6063 |
| CAS | 1073154-85-4 |
| MW: | 510.49 D |
From 30.00€
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