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NPPB
Item number: TGM-T7638-100mg
Description: NPPB is a chloride channel blocker with IC50 of 80 nM . Target: Chloride channel. Smiles: OC(=O)c1cc(ccc1NCCCc1ccccc1)[N+]([O-])=O. References: Taniguchi Y , Tonai-Kachi H , Shinjo K . 5-Nitro-2-(3-Phenylpropylamino)benzoic Acid Is a GPR35 Agonist[J]. Pharmacology, 2008, 82(4):245-249.
| Application: | GPR35 agonist, chloride channel blocker |
| CAS | 107254-86-4 |
| MW: | 300.31 D |
From 49.00€
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NPPB
Item number: Cay17292-10
NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. It has been shown to activate the GPR35-Galphai/o and GPR35-Galpha16 pathways in HEK293 cells, inducing intracellular calcium mobilization. NPPB has protonophoric activity and has been used to uncouple mitochondrial...
| Keywords: | HOE 144, Hoechst 144, 5-nitro-2-[(3-phenylpropyl)amino]-benzoic acid |
| Application: | GPR35 agonist, chloride channel blocker |
| CAS | 107254-86-4 |
| MW: | 300.3 D |
From 77.00€
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