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Item number: Cay21239-100

Granisetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 3.9 nM) with antiemetic activity. It is selective for 5-HT3 over 5-HT4 receptors (Ki = >1,000 nM). Granisetron (0.3, 1, and 3 mg/kg, p.o.) increases the latency to first vomiting episode and reduces the number of vomiting episodes in a...

Keywords:	BRL 43694, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide, monohydrochloride
Application:	5-HT3 receptor antagonist
CAS	107007-99-8
MW:	348.9 D

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