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Item number: TGM-T13083-10mg

Description: Tafenoquine is an 8-aminoquinoline,and is an agent of anti-malarial prophylactic. Target: Others. Smiles: O(C=1C2=C(C(NC(CCCN)C)=CC1OC)N=C(OC)C=C2C)C3=CC(C(F)(F)F)=CC=C3. References: Marcsisin SR, et al. Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the...

Keywords:	WR 238605
Application:	Antimalarial
CAS	106635-80-7
MW:	463.49 D

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Tafenoquine

Item number: Cay30673-10

Tafenoquine is an aminoquinoline antimalarial agent. It is active against multidrug-resistant clinical isolates of P. falciparum (IC50s = 64.6-110.4 ng/ml). Tafenoquine (25 or 50 mg/kg) inhibits sporozoite transmission to mosquitos fed on P. berghei-infected mice. It also suppresses parasitemia in a hamster model of...

Keywords:	WR 238605, N4-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl]-1,4-pentanediamine
Application:	Antimalarial agent
CAS	106635-80-7
MW:	463.5 D

From 106.00€ *

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