2 products were found matching "1062169-56-5"!
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WYE-354
Item number: Cay13604-10
WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-kinase alpha (IC50 = 1,026 nM) and other kinases. WYE-354 induces G1 cell cycle arrest in both rapamycin-sensitive and...
| Keywords: | 4-[6-[4-[(methoxycarbonyl)amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylic acid,... |
| Application: | mTOR inhibitor |
| CAS | 1062169-56-5 |
| MW: | 495.5 D |
From 139.00€
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WYE-354
Item number: TGM-T6731-100mg
Description: WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kalpha (>100-fold) and PI3Kgamma (>500-fold). Target: Autophagy, mTOR, PI3K, Apoptosis. Smiles:...
| Application: | mTOR inhibitor |
| CAS | 1062169-56-5 |
| MW: | 495.53 D |
From 41.00€
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