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5-OxoETE
5-OxoETE

Item number: Cay34250-25

5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase. It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway...
Keywords: 5-KETE, 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid
Application: Polyunsaturated keto acid, neutrophil migration stimulator
CAS 106154-18-1
MW: 318.5 D
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