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Item number: Cay27655-1

Anlotinib is an orally bioavailable tyrosine kinase inhibitor that inhibits human VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, and c-Kit (IC50s = 26.9, 0.2, 0.7, 115, and 14.8 nM, respectively). It is selective for these kinases over c-Met, c-Src, HER2, and EGFR (IC50s = >2,000 nM). It also inhibits FGFR1 (IC50 = 11.7 nM for...

Keywords:	1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]-cyclopropanamine, monohydrochloride
Application:	Tyrosine kinase inhibitor
CAS	1058157-76-8
MW:	443.9 D

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