- Search results for 104987-11-3
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5 products were found matching "104987-11-3"!
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Item number: Cay10007965-5
FK-506 is a potent immunosuppressant in the same molecular class as cyclosporin A (Cay-12088) and rapamycin (Cay-13346). Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex then inhibits the activity of the...
Keywords: | Tacrolimus,... |
Application: | Immunosuppressant |
CAS | 104987-11-3 |
MW: | 804 D |
From 48.00€
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Item number: F4522-01.50
FK-506 is a potent immunosuppressant and in vitro T cell proliferation blocker. It has been shown to disrupt calcineurin (also known as CaN or phosphatase 2B)-mediated signal transduction in T lymphocytes. The compound interacts with its FK506-binding protein-12 (FKBP12). The resulting complex, in turn,...
CAS | 104987-11-3 |
MW: | 804.02 |
From 216.00€
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Item number: LKT-T0008.5
An immunosuppressant commonly used in transplant operations to prevent graft-versus-host disease.
Keywords: | FK506, FK-506, fujimycin |
Application: | Immunomodulator |
CAS | 104987-11-3 |
MW: | 804,02 D |
From 60.00€
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Item number: AG-CN2-0047-M001
Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Forms a complex with FK-506 binding protein 12 (FKBP12). Inhibits the activity of the calcium/calmodulin-dependent protein...
Keywords: | Tacrolimus, Fujimycin |
Application: | Immunosuppressant |
Host: | Streptomyces FCZ0311 |
CAS | 104987-11-3 |
From 17.00€
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Item number: LC-F-4900_50mg
Soluble in DMSO at 100 mg/mL, soluble in ethanol at 100 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Keywords: | Tacrolimus,... |
Application: | Immunosuppressant |
CAS | 104987-11-3 |
MW: | 804,02 D |
From 109.00€
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