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Item number: TGM-T26684-100mg

Description: Auten-99 HBr (Auten-99) is a myotubularin phosphatase Jumpy inhibitor exerting potent neuroprotective effects. AUTEN-99 activates autophagy in cell cultures and animal models. AUTEN-99 appears to effectively penetrate through the blood-brain barrier, and impedes the progression of neurodegenerative...

Keywords:	Auten-99 hydrochloride. Auten-99 HBr, Auten-99, Auten99, Auten 99
CAS	1049780-58-6
MW:	359.28 D

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AUTEN-99

Item number: Cay30047-5

AUTEN-99 is an inhibitor of the phosphatase myotubularin-related protein 14 (MTMR14/Jumpy). It inhibits MTMR14/Jumpy activity in a cell-free assay when used at concentrations of 10 and 100 µM. AUTEN-99 (1 and 10 µM) enhances autophagic flux and increases the levels of LC3B-11 in HeLa cells. It increases survival of...

Keywords:	Autophagy Enhancer-99, 2-[1,1'-biphenyl]-4-yl-5,6-dihydro-imidazo[2,1-b]thiazole, monohydrobromide
Application:	MTMR14 inhibitor
CAS	1049780-58-6
MW:	359.3 D

From 44.00€ *

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