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Item number: LKT-N3476.50

Nitisinone is a nitrobenzene inhibitor of HPPD, an enzyme involved in tyrosine degradation. Nitisinone is clinically used to slow the effects of hereditary type 1 tyrosinemia and as a potential treatment for alkaptonuria.

Keywords:	NTBC, orfadin
Application:	4-hydroxyphenylpyruvate dioxygenase inhibitor
CAS	104206-65-7
MW:	329.23 D

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Nitisinone

Item number: Cay17924-50

Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway. Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3...

Keywords:	NTBC, SC-0735, 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione
Application:	Reversible 4-hydroxyphenylpyruvate dioxygenase inhibitor
CAS	104206-65-7
MW:	329.2 D

From 43.00€ *

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