2 products were found matching "1039455-84-9"!

No results were found for the filter!

Item number: TGM-T4325-100mg

Description: COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity. Target: Apoptosis, p53. Smiles: S=C(N\N=C1/CCCc2cccnc12)N1CCN(CC1)c1ccccn1. References: Bykov VJN,etal.Targeting mutant p53 for efficient cancer therapy.Nat Rev...

Keywords:	COTI2, COTI 2
Application:	Mutant p53 activator
CAS	1039455-84-9
MW:	366.48 D

From 40.00€ *

Show details

Review

COTI-2

Item number: Cay20031-1

COTI-2 is an orally available thiosemicarbazone that activates mutant forms of p53. It induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines more effectively than cetuximab and erlotinib (Cay-10483), and is active against human glioblastoma...

Keywords:	4-(2-pyridinyl)-2-(6,7-dihydro-8(5H)-quinolinylidene)hydrazide-1-piperazinecarbothioic acid
Application:	Mutant p53 activator
CAS	1039455-84-9
MW:	366.5 D

From 44.00€ *

Show details

Review

Didn't find the right Product? Here are some useful Search Tips!

Checklist-Thumbnail

All our products have English titles and descriptions. Therefore, use English search terms.
Write out Greek letters - i.e. "alpha" instead of α or "beta" instead of β.
Do not add "and" when entering multiple search terms.
Use the singular (e.g. "antibody" instead of "antibodies").
If available, try synonyms (e.g. for a specific protein).
You can search for chemical substances using the unique CAS number (Chemical Abstracts Service).
In addition, you can also use the UniProt or KEGG accession number for the product search.
Use our filter function to narrow down your search results. If you want to remove a selected filter again, click on the small "x" next to the filter.
Are you looking for products from a specific supplier? Then enter the corresponding supplier name and select it in the appearing suggestion field. Alternatively, you can also use our supplier overview.
Use - if known - the specific product number. Especially for short numbers, note the supplier code in front of each number for most of our partners (e.g. for AAT Bioquest "ABD-121" instead of just "121"). Click on the button below to find all supplier codes and additional information.

All Supplier Codes

We would be very happy to support you in your product search! Contact us at info@biomol.com.