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Item number: Cay13687-1

Two Rho-associated kinases (ROCK), ROCK1 and ROCK2, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. CAY10622 is a potent, ureidobenzamide...

Keywords:	3-[[[[[4-(aminocarbonyl)phenyl]amino]carbonyl]amino]methyl]-N-(1,2,3,4-tetrahydro-7-isoquinolinyl)-benzamide
Application:	Rock kinase inhibitor
CAS	1038549-25-5
MW:	443.5 D

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ROCK-IN-10

Item number: TGM-T84502-10mg

Description: ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1]. Target: Others. Smiles:...

Application:	Rock kinase inhibitor
CAS	1038549-25-5
MW:	443.507 D

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