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JPH203
Item number: TGM-TQ0081-100mg
Description: JPH203 (KYT-0353) is a potent and specific inhibitor of L-type amino acid transporter protein 1 (LAT-1). JPH203 inhibits cellular uptake of leucine, inhibits cell proliferation, induces apoptosis, and possesses anti-inflammatory and anti-tumor activities. Target: Others. Smiles:...
| Keywords: | KYT-0353 |
| Application: | L-type amino acid transporter 1 (LAT1) inhibitor |
| CAS | 1037592-40-7 |
| MW: | 472.32 D |
From 43.00€
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JPH203
Item number: Cay29715-5
JPH203 is an inhibitor of L-type amino acid transporter 1 (LAT1, IC50 = 0.14 µM for 14C-leucine uptake in S2 cells expressing the human transporter). It is selective for LAT1 over LAT2 (IC50 = >10 µM). JPH203 inhibits 14C-leucine uptake by, and growth of, HT-29 cells (IC50s = 0.06 and 4.1 µM, respectively). It...
| Keywords: | KYT-0353, O-[(5-amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine |
| Application: | L-type amino acid transporter 1 (LAT1) inhibitor |
| CAS | 1037592-40-7 |
| MW: | 472.3 D |
From 44.00€
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