2 products were found matching "1033735-94-2"!
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GNE-493
Item number: SYN-1115-M001
Soluble in DMSO. GNE-493 is a potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitor for the treatment of cancer. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Keywords: | GNE493 |
| Application: | PI3K inhibitor |
| CAS | 1033735-94-2 |
| MW: | 372,4 D |
From 250.00€
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GNE-493
Item number: Cay29224-1
GNE-493 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR, IC50s = 3.4, 12, 16, 16, and 32 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma, and mTOR, respectively). It inhibits proliferation of PC3 and MCF-7.1 cells with IC50 values of 330 and 180 nM, respectively. GNE-493 (10 mg/kg per day)...
| Keywords: | 2-(2-amino-5-pyrimidinyl)-alpha,alpha-dimethyl-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine-6-methanol |
| Application: | PI3K / mTOR dual inhibitor |
| CAS | 1033735-94-2 |
| MW: | 372.4 D |
From 163.00€
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