3 products were found matching "1033735-94-2"!
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GNE-493
Item number: SYN-1115-M001
Soluble in DMSO. GNE-493 is a potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitor for the treatment of cancer. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Keywords: | GNE493 |
| Application: | PI3K inhibitor |
| CAS | 1033735-94-2 |
| MW: | 372,4 D |
From 293.00€
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GNE-493
Item number: TGM-T7166-100mg
Description: GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma and mTOR,respectively. Target: mTOR, PI3K. Smiles: CC(C)(O)c1cc2nc(nc(N3CCOCC3)c2s1)-c1cnc(N)nc1....
| Application: | PI3K / mTOR dual inhibitor |
| CAS | 1033735-94-2 |
| MW: | 372.44 D |
From 39.00€
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GNE-493
Item number: Cay29224-1
GNE-493 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR, IC50s = 3.4, 12, 16, 16, and 32 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma, and mTOR, respectively). It inhibits proliferation of PC3 and MCF-7.1 cells with IC50 values of 330 and 180 nM, respectively. GNE-493 (10 mg/kg per day)...
| Keywords: | 2-(2-amino-5-pyrimidinyl)-alpha,alpha-dimethyl-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine-6-methanol |
| Application: | PI3K / mTOR dual inhibitor |
| CAS | 1033735-94-2 |
| MW: | 372.4 D |
From 40.00€
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