4 products were found matching "1032900-25-6"!
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Ceritinib
Item number: Cay19374-1
Ceritinib is an inhibitor of anaplastic lymphoma kinase (ALK, IC50 = 0.2 nM). It is selective for ALK over IGF-1R, InsR, STK22D, and FLT3 (IC50s = 8, 7, 23, and 60 nM, respectively) as well as a panel of 25 additional kinases (IC50s = >0.26 µM for all). Ceritinib inhibits the proliferation of Ba/F3 cells expressing...
| Keywords: | LDK 378,... |
| Application: | ALK inhibitor |
| CAS | 1032900-25-6 |
| MW: | 558.1 D |
From 39.00€
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LDK378
Item number: LKT-L1340.1
LDK378 is a selective inhibitor of ALK1, a target found in metastatic non-small cell lung cancer (NSCLC).
| Keywords: | LDK-378, 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine |
| Application: | ALK1 inhibitor |
| CAS | 1032900-25-6 |
| MW: | 558.13 D |
From 79.00€
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LDK378
Item number: SYN-1199-M001
Soluble in DMSO (heat) or ethanol. LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively. Target: ALK , Kinase Group: RTK , Substrate: Tyrosine
| Keywords: | LDK-378 |
| Application: | ALK inhibitor |
| CAS | 1032900-25-6 |
| MW: | 558,1 D |
From 79.00€
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Ceritinib, Free Base
Item number: LC-C-2086_100mg
Soluble in DMSO
| Keywords: | LDK 378,... |
| Application: | ALK inhibitor |
| CAS | 1032900-25-6 |
| MW: | 558,14 D |
From 99.00€
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