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Item number: Cay26181-5

GSK1292263 is an agonist of G protein-coupled receptor 119 (GPR119, EC50 = 43.9 nM in CHO-K1 cells expressing human receptors). It inhibits increases in sterol regulatory element binding protein-1 (SREBP-1) levels induced by the LXR agonist T0901317 and increases activation of AMPK in HepG2 cells in a...

Keywords:	5-[[1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl]methoxy]-2-[4-(methylsulfonyl)phenyl]-pyridine
Application:	GPR119 agonist
CAS	1032823-75-8
MW:	456.6 D

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