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MK-2206 (hydrochloride)
MK-2206 (hydrochloride)

Item number: Cay11593-1

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBalpha, beta, gamma) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK-2206 is an orally active, allosteric Akt inhibitor that is equally potent toward purified human recombinant Akt1 and Akt2...
Keywords: 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, dihydrochloride
Application: Allosteric Akt inhibitor
CAS 1032350-13-2
MW: 480.4 D
From 58.00€ *
Review
COVID-19 Research
MK2206 (dihydrochloride)
MK2206 (dihydrochloride)

Item number: LKT-M4000.1

MK2206 is a Akt inhibitor, is also an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds to and inhibits the activity of Akt in a non-ATP competitive manner, which may result in the inhibition of...
Keywords: MK-2206 . 2HCl, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-8,9-dihydro-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one...
Application: AKT inhibitor
CAS 1032350-13-2
MW: 445.94 D
From 79.00€ *
Review
MK-2206
MK-2206

Item number: SYN-1162-M005

Soluble in DMSO or ethanol. MK-2206 is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC(50) of 8nM, 12nM and 65nM, respectively. Target: AKT , Kinase Group: AGC , Substrate: Serine-Threonine
Keywords: MK2206
Application: AKT inhibitor
CAS 1032350-13-2
MW: 480,4 D
From 92.00€ *
Review
COVID-19 Research
MK-2206 Dihydrochloride
MK-2206 Dihydrochloride

Item number: LKT-M400220.100

Akt inhibitor.
Keywords: MK-2206 hydrochloride
Application: Allosteric Akt inhibitor
CAS 1032350-13-2
MW: 480.39 D
From 76.00€ *
Review