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Item number: Cay27684-1

CIM0216 is a transient receptor potential melastatin 3 (TRPM3) activator. It induces inward and outward rectifying currents in TRPM3-expressing HEK293 cells voltage-clamped at ±80 mV when used at a concentration of 1 µM. CIM0216 is selective for TRMP3 over TRPM1, TRPM4, TRPM6, and TRMP7 in HEK293 cells expressing...

Keywords:	3,4-dihydro-N-(5-methyl-3-isoxazolyl)-alpha-phenyl-1(2H)-quinolineacetamide
Application:	TRPM3 activator
CAS	1031496-06-6
MW:	347.4 D

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cim0216

Item number: TGM-T9263-100mg

Description: CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist. Target: TRP/TRPV Channel. Smiles: Cc1cc(NC(=O)C(N2CCCc3ccccc23)c2ccccc2)no1. References: Vriens J , Owsianik G , Hofmann T , et al. TRPM3 is a nociceptor channel involved in...

Keywords:	N-(5-methyl-1,2-oxazol-3-yl)-2-phenyl-2-(1,2,3,4-tetrahydroquinolin-1-yl)acetamide
Application:	TRPM3 activator
CAS	1031496-06-6
MW:	347.41 D

From 38.00€ *

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