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HS-38
Item number: Cay42246-5
A DAPK1 (IC50 = 200 nM) and DAPK3 inhibitor, selectively binds to DAPK1, DAPK2, and DAPK3 (Kds = 300, 79, and 280 nM, respectively) over Pim-1, Pim-2, and Pim-3 (Kds = 1,800, 6,500, and 810 nM, respectively) but does inhibit Pim-3 (IC50 = 200 nM), inhibits phosphorylation of RLC20 in primary human coronary artery...
| Keywords: | 2-[[1-(3-chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]-propanamide |
| Application: | DAPK1/DAPK3 inhibitor |
| CAS | 1030203-81-6 |
| MW: | 349.8 D |
From 50.00€
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HS38
Item number: TGM-T27554-100mg
Description: HS38 is a specific and ATP-competitive DAPK inhibitor with Kds of 300 nM, 200 nM, and 280 nM for DAPK1, PIM3, and ZIPK. HS38 can be used in studies about smooth muscle-related disorders. Target: DAPK. Smiles: CC(Sc1nc2n(ncc2c(=O)[nH]1)-c1cccc(Cl)c1)C(N)=O. References: MacDonald JA, et al. A Small...
| Keywords: | HS 38, HS-38 |
| CAS | 1030203-81-6 |
| MW: | 349.8 D |
From 45.00€
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