4 products were found matching "1028486-01-2"!
No results were found for the filter!
MLN8237
Item number: Cay13602-1
MLN8237 is an inhibitor of Aurora A kinase (IC50 = 1 nM). It is selective for Aurora A over Aurora B kinase (IC50 = 396.5 nM). MLN8237 (50 nM) induces cell cycle arrest at the G2/M phase and chromosomal misalignment in HCT116 colon cancer cells. It inhibits tumor growth in a Calu-6 non-small cell lung cancer (NSCLC)...
| Keywords: | Alisertib, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy benzoic acid |
| Application: | Aurora A kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.9 D |
From 49.00€
*
MLN8237
Item number: LKT-M4652.10
MLN8237 inhibits aurora kinase A (AurA) preventing mitotic spindle formation and proper completion of mitosis. MLN8237 exhibits anticancer chemotherapeutic activity and is currently in clinical trials as a potential treatment for multiple myeloma, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia (CLL). In...
| Keywords: | Alisertib |
| Application: | Aurora A kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.92 D |
From 164.00€
*
MLN 8237
Item number: 281903.10
MLN8237 (Alisertib) is an orally available selective aurora A kinase inhibitor.
| Keywords: | 4-[[9-Chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-benzoic acid, Alisertib,... |
| Application: | Antineoplastic, Serine/threonine kinase inhibitor, Aurora kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.92 D |
460.00€
*
Alisertib
Item number: TGM-T2241-100mg
Description: Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B. Target: Apoptosis, Autophagy, Aurora Kinase. Smiles: COc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(O)=O. References: Görgün G, et al....
| Keywords: | MLN 8237 |
| Application: | Targets aurora kinase A [EC:2.7.11.1] (AURKA) |
| CAS | 1028486-01-2 |
| MW: | 518.92 D |
From 48.00€
*
