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Item number: Cay42392-10

A DP2/CRTH2 and DP1 dual antagonist (IC50s = 3 and 12 nM, respectively), decreases airway resistance in a guinea pig model of aerosolized PGD2-induced airflow obstruction at 3, 10, and 30 mg/kg. Formulation: A solid. InChI:...

Keywords:	4-[4-[(butylamino)carbonyl]-2-[[(2,4- dichlorophenyl)sulfonyl]amino]phenoxy]- 3-methoxy-benzeneacetic acid
Application:	Prostaglandin D2 receptor 2 (CRTH2) / PTGDR (Prostaglandin DP1 receptor) dual antagonist
CAS	1027847-67-1
MW:	581.5 D

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AMG-009

Item number: TGM-T14211-100mg

Description: AMG-009 is a selective and potent dual antagonist of CRTH2 and DP, with an IC50 value of 3 nM for CRTH2 and 12 nM for DP receptors. Target: GPR, Prostaglandin Receptor. Smiles: O=C(O)CC1=CC=C(OC2=CC=C(C=C2NS(=O)(=O)C3=CC=C(Cl)C=C3Cl)C(=O)NCCCC)C(OC)=C1. References: Liu J, et al. Discovery and...

CAS	1027847-67-1
MW:	581.47 D

From 39.00€ *

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