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CINPA1
Item number: Cay29110-1
CINPA1 is a constitutive androstane receptor (CAR) antagonist (IC50 = 70 nM in a reporter assay). It is selective for CAR over the nuclear receptors GR, FXR, LXRalpha, LXRbeta, PPARgamma, RXRalpha, and RXRbeta at 18 µM, but also antagonizes the human pregnane X receptor (PXR, IC50 = 6.6 µM). CINPA1 (0.3-5 µM)...
| Keywords: | [5-[(diethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]-carbamic acid, ethyl ester |
| Application: | Constitutive androstane receptor (CAR) antagonist |
| CAS | 102636-74-8 |
| MW: | 395.5 D |
From 51.00€
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CINPA1
Item number: TGM-T14969-10mg
Description: CINPA1 (CINPA 1) is a selective inhibitor of constitutive androstane receptor (CAR) with an IC50 of 70 nM for CAR-mediated transcription. CINPA1 can be used in studies about CAR function. Target: Others. Smiles: CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CN(CC)CC)c2c1. References: Cherian MT, et al. CINPA1 is an...
| Keywords: | CINPA 1, CINPA-1 |
| Application: | Constitutive androstane receptor (CAR) antagonist |
| CAS | 102636-74-8 |
| MW: | 395.49 D |
From 30.00€
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