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Item number: Cay22588-10

Lifitegrast is an inhibitor of the protein-protein interaction between lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1). It binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits the...

Keywords:	SAR 1118,...
Application:	CD11A blocker
CAS	1025967-78-5
MW:	615.5 D

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