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R788 (sodium salt)
Item number: Cay18501-5
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs of FcRgamma chains and mediates downstream signaling related to platelet function and inflammation. R788 is a prodrug of R406 (Cay-11422), an inhibitor of Syk (Ki = 30...
| Keywords: | Fostamatinib, NSC 745942, R935788, Tamatinib Fosdium,... |
| Application: | R406 prodrug, Syk inhibitor |
| CAS | 1025687-58-4 |
| MW: | 624.4 D |
From 60.00€
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R788 disodium salt
Item number: SYN-1122-M001
Slightly soluble (<1mg/ml) in DMSO or ethanol. Tamatinib effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals. Target: BCR , Kinase Group: PTK , Substrate: Tyrosine
| Keywords: | Fostamatinib, Tamatinib fosdium, FosD, R-788 |
| Application: | Syk inhibitor |
| CAS | 1025687-58-4 |
| MW: | 624,5 D |
From 139.00€
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