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Item number: TGM-T1634-500mg

Description: Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide. Target: P-gp, Mitochondrial Metabolism, CFTR, Autophagy, Potassium Channel. Smiles: C(NCCC1=CC=C(S(NC(NC2CCCCC2)=O)(=O)=O)C=C1)(=O)C3=C(OC)C=CC(Cl)=C3. References: Winquist RJ, et...

Keywords:	Glyburide
Application:	Antidiabetic, Hypoglycemic
CAS	10238-21-8
MW:	494 D

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Glyburide

Item number: AG-CR1-3613-G001

White to off-white solid. Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol (gentle warming). Antidiabetic compound, Binds to and activates the ATP-sensitive potassium channels (KATP) inhibitory regulatory subunit sulfonylurea receptor 1 (SUR1), Causes cell membrane depolarization and opening of...

Keywords:	Diabeta, Glibenclamide
Application:	Antidiabetic compound, SUR1 activator
CAS	10238-21-8
MW:	494,0 D

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