2 products were found matching "1020315-31-4"!

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Item number: Cay19306-5

PF-04457845 is an orally active, irreversible inhibitor of fatty acid amide hydrolase (FAAH, IC50 = 7.2 nM) that is selective against other serine hydrolases. It is a covalent inhibitor that carbamylates the active site serine nucleophile of FAAH. In a rat model of inflammatory pain, oral administration of 0.1 mg/kg...

Keywords:	N-3-pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide
Application:	Irreversible FAAH inhibitor
CAS	1020315-31-4
MW:	455.4 D

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PF-04457845

Item number: TGM-T4323-100mg

Description: PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM). Target: FAAH, Autophagy. Smiles: FC(F)(F)c1ccc(Oc2cccc(C=C3CCN(CC3)C(=O)Nc3cccnn3)c2)nc1. References: Johnson DS, et al. Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and...

Keywords:	PF 04457845, PF04457845
Application:	Irreversible FAAH inhibitor
CAS	1020315-31-4
MW:	455.43 D

From 30.00€ *

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