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Item number: TGM-T17284-1mL

Description: Zardaverine (BY 290) is an orally available, selective and potent PDE3/4 inhibitor with bronchodilator activity and anti-hepatocarcinogenic activity.Zardaverine's action in platelets is mediated by PDE III isoenzymes and can be used in studies of acute renal failure and chronic airflow obstruction....

Keywords:	BY 290, B 84290
Application:	PDE3 / PDE4 dual inhibitor
CAS	101975-10-4
MW:	268.22 D

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Zardaverine

Item number: Cay29685-1

Zardaverine is a dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 (IC50s = 0.617 and 1.738 µM, respectively, for the rat cardiac ventricle enzymes). It is selective for PDE3 and PDE4 over PDE1B, PDE2, and PDE5 (IC50s = >138 µM for all). Zardaverine inhibits aggregation of human platelets induced by ADP...

Keywords:	6-[4-(difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone
Application:	PDE3 / PDE4 dual inhibitor
CAS	101975-10-4
MW:	268.2 D

From 44.00€ *

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