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Item number: Cay18497-1

S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH, particularly in myocytes. It inhibits intracellular pH recovery in myocytes with a Ki value of 1.7 µM, with full inhibition occurring at ~30 µM. S0859 does not affect other...

Keywords:	2-chloro-N-[[2'-[(cyanoamino)sulfonyl][1,1'-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]-benzamide
Application:	SLC4A7 blocker
CAS	1019331-10-2
MW:	530 D

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S0859

Item number: TGM-T2010-100mg

Description: S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH. Target: Others. Smiles: Cc1ccc(CN(Cc2ccc(cc2)-c2ccccc2S(=O)(=O)NC#N)C(=O)c2ccccc2Cl)cc1. References: Larsen AM, et al. ChemMedChem. 2012 Oct,7(10):1808-14.

CAS	1019331-10-2
MW:	530.04 D

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