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Item number: Cay26257-10

CC-122 is a pleiotropic pathway modifier with anticancer activity. It binds to cereblon, a substrate receptor protein of the Cullin 4 RING E3 ubiquitin ligase complex, in U266 multiple myeloma cell extracts and induces recruitment and degradation of the cereblon substrates Aiolos and Ikaros in TMD8, OCI-LY10, and...

Keywords:	Avadomide, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-2,6-piperidinedione
Application:	Antineoplastic, immunomodulator
CAS	1015474-32-4
MW:	286.3 D

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3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2...

Item number: BPS-82012

3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione has been shown to treat Diffuse large B-cell lymphoma with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon, a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4.

Application:	Protac(R) reagent
CAS	1015474-32-4
MW:	286,3 D

1,343.00€ *

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