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Item number: TGM-T9465-100mg

Description: ZZW-115 hydrochloride inhibits the activity of NUPR1. Target: Apoptosis, Others. Smiles: Cl.Cl.Cl.CN(C)CCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1. References: Santofimia-Castaño P, et al. Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis. J Clin...

Application:	NUPR1 inhibitor
CAS	10122-45-9
MW:	573.97 D

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ZZW-115

Item number: Cay34974-10

ZZW-115 is an inhibitor of nuclear protein 1 (NUPR1). It binds to NUPR1 (Kd = 2.1 µM) in a cell-free assay. ZZW-115 is cytotoxic against a panel of 11 pancreatic ductal adenocarcinoma cell lines (IC50s = 0.84-4.93 µM), as well as against a panel of 16 additional cancer cell lines, including glioblastoma, lymphoma,...

Keywords:	N,N-dimethyl-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanamine, trihydrochloride
Application:	NUPR1 inhibitor
CAS	10122-45-9
MW:	574 D

From 75.00€ *

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