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CUDC-101
Item number: Cay16426-10
CUDC-101 is a multi-target inhibitor, combining functional groups of potent inhibitors of human epidermal growth factor receptor (HER) kinases and histone deacetylases (HDACs). It potently blocks the receptor tyrosine kinases EGFR (aka HER1) and HER2 (IC50s = 2.4 and 16.4 nM, respectively). CUDC-101 also inhibits...
| Keywords: | 7-[[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-hydroxy-heptanamide |
| Application: | Multi-target (EGFR, HER2, HDAC) inhibitor |
| CAS | 1012054-59-9 |
| MW: | 434.5 D |
From 110.00€
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CUDC-101
Item number: TGM-T3108-100mg
Description: CUDC-101 is a potent inhibitor of HDAC, EGFR, and HER2 with IC50s of 4.4 nM, 2.4 nM, and 15.7 nM, respectively. Target: HDAC, HER, EGFR. Smiles: N(C=1C2=C(C=C(OC)C(OCCCCCCC(NO)=O)=C2)N=CN1)C3=CC(C#C)=CC=C3. References: Cai X, et al. J Med Chem, 2010, 53(5), 2000-2009.
| Keywords: | CUDC101, CUDC 101 |
| Application: | Multi-target (EGFR, HER2, HDAC) inhibitor |
| CAS | 1012054-59-9 |
| MW: | 434.49 D |
From 41.00€
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