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CX-4945
CX-4945

Item number: Cay16779-10

CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2, Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2alpha subunit, conferring selectivity. It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of...
Keywords: Silmitasertib, 5-[(3-chlorophenyl)amino]-benzo[c]-2,6-naphthyridine-8-carboxylic acid
Application: CK2 inhibitor
CAS 1009820-21-6
MW: 349.8 D
From 84.00€ *
Review
CX-4945 . hydrochloride [Silmitasertib . HCl]
CX-4945 . hydrochloride [Silmitasertib . HCl]

Item number: AG-CR1-3629-M005

Yellow solid. Soluble in DMSO. Insoluble in water. Orally active, potent and selective ATP-competitive inhibitor of the protein kinase CK2 (IC50=1nM), Anticancer compound. Inhibits proliferation in a panel of cancer cell lines that overexpress CK2. Inhibited migration, blocks survival and induces apoptosis in cancer...
Keywords: Silmitasertib . HCl, 8-Carboxy-N-(3-chlorophenyl)benzo[c][2,6] naphthyridin-5-aminium chloride
Application: Protein kinase CK2 inhibitor
CAS 1009820-21-6
MW: 386,3 D
From 77.00€ *
Review