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Item number: Cay37748-5

SB-4 is an activator of bone morphogenetic protein 4 (BMP4) signaling. It induces BMP4 signaling in a reporter assay using HEK293 cells expressing a recombinant human BMP4 response element (EC50 = 74 nM). SB-4 (10 µM) increases phosphorylation of SMAD1, -5, and -9 in HEK293 cells. It also induces Blimp1 and Tfap2c...

Keywords:	2-[[(4-bromophenyl)methyl]thio]-benzoxazole
Application:	BMP4 signaling activator
CAS	100874-08-6
MW:	320.2 D

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BMP signaling agonist sb4

Item number: TGM-T7799-100mg

Description: BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM). Target: TGF-beta/Smad. Smiles: Brc1ccc(CSc2nc3ccccc3o2)cc1. References: Bradford S T J , Ranghini E J , Grimley E , et al. High-throughput screens for agonists of bone morphogenetic...

Keywords:	SB 4
Application:	BMP4 signaling activator
CAS	100874-08-6
MW:	320.2 D

From 38.00€ *

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