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ML-346
Item number: Cay23844-1
ML-346 is an activator of the heat shock response that induces the expression of the heat shock proteins HSP70, HSP40, and HSP27. It induces the expression of the oxidative stress response genes HO1, GCLM, and BiP in mouse embryonic fibroblasts (MEFs) and pretreatment protects cells from severe heat shock-induced...
| Keywords: | 5-[3-(4-methoxyphenyl)-2-propen-1-ylidene]-2,4,6(1H,3H,5H)-pyrimidinetrione |
| Application: | Heat shock response activator, HSP70 / HSP40 / HSP27 expression inducer |
| CAS | 100872-83-1 |
| MW: | 272.3 D |
From 56.00€
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ML346
Item number: TGM-T3594-100mg
Description: ML346 is a novel activator of Hsp70. Target: HSP. Smiles: COc1ccc(\C=C\C=C2C(=O)NC(=O)NC2=O)cc1. References: Calamini B,et al. ML346: A Novel Modulator of Proteostasis for Protein Conformational Diseases. National Center for Biotechnology Information (US), 2010-2012 Dec 17.
| Application: | Heat shock response activator, HSP70 / HSP40 / HSP27 expression inducer |
| CAS | 100872-83-1 |
| MW: | 272.26 D |
From 33.00€
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