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LCL161
LCL161

Item number: TGM-T2080-100mg

Description: LCL161, a SMAC mimetic, effectivity binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). Target: IAP. Smiles: CNC(C)C(=O)NC(C1CCCCC1)C(=O)N1CCCC1c1nc(cs1)C(=O)c1ccc(F)cc1. References: Weisberg E, et al. Leukemia, 2010, 24(12), 2100-2109.
CAS 1005342-46-0
MW: 500.63 D
From 62.00€ *
Review
LCL-161
LCL-161

Item number: Cay22420-5

LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins. As a single agent, LCL-161 inhibits growth of FLT3-ITD-expressing leukemia cells via induction of apoptosis with IC50 values ranging from 0.5-4 µM. In vivo, LCL-161 enhances growth inhibition driven by PKC...
Keywords: NVP-LCL161,...
Application: DIABLO / SMAC mimetic, IAP inhibitor
CAS 1005342-46-0
MW: 500.6 D
From 219.00€ *
Review
LCL-161
LCL-161

Item number: LKT-L1044.1

SMAC mimetic, PXR agonist, IAP inhibitor.
Keywords: LCL161
Application: DIABLO / SMAC mimetic, IAP inhibitor
CAS 1005342-46-0
MW: 500.63 D
From 121.00€ *
Review
LCL-161
LCL-161

Item number: BPS-82073

LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitors of apoptosis (IAP) family proteins.
Keywords: LCL161, LCL 161,
Application: Smac mimetic, IAP inhibitor
CAS 1005342-46-0
MW: 500,9 D
859.00€ *
Review