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MX69
Item number: Cay27224-5
MX69 is an inhibitor of the interaction between the ubiquitin ligase MDM2 protein and XIAP mRNA. It binds to the RING domain of MDM2 (Kd = 2.34 µM) and decreases the levels of MDM2 and XIAP in a concentration-dependent manner without affecting the levels of Bcl-2, cIAP-1, and cIAP-2. It induces autoubiquitination...
| Keywords: | 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-benzoic acid |
| Application: | MDM2 protein - XIAP mRNA interaction inhibitor |
| CAS | 1005264-47-0 |
| MW: | 474.6 D |
From 73.00€
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MX69
Item number: TGM-T3653-100mg
Description: MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. Target: IAP, Mdm2, E1/E2/E3 Enzyme, MDM-2/p53. Smiles: Cc1ccc(NS(=O)(=O)c2ccc3NC(C4CC=CC4c3c2)c2ccc(cc2)C(O)=O)cc1C
| Application: | MDM2 protein - XIAP mRNA interaction inhibitor |
| CAS | 1005264-47-0 |
| MW: | 474.57 D |
From 34.00€
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