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Item number: Cay43043-10

TH10785 is an 8-oxoguanine DNA glycosylase 1 (OGG1) activator. It increases OGG1-mediated excision of 8-oxoguanine (8-hydroxyguanine, Cay-89290) in duplex oligonucleotides when used at a concentration of 10 µM. TH10785 (10, 30, or 100 µM) inhibits oxidative damage in A549 cells induced by paraquat (Cay-38521). It...

Keywords:	N-cyclohexyl-2-cyclopropyl-4-quinazolinamine
Application:	OGG1 activator
CAS	1002801-51-5
MW:	267.38 D

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TH1085

Item number: TGM-T60034-100mg

Description: TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ). Target: Others. Smiles: C1CC1c1nc(NC2CCCCC2)c2ccccc2n1. References: Baptiste BA, et al. Enhanced mitochondrial DNA repair of the common disease-associated variant, Ser326Cys, of...

CAS	1002801-51-5
MW:	267.37 D

From 42.00€ *

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