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AMG 208
AMG 208

Item number: Cay24197-1

AMG 208 is a potent inhibitor of c-Met (IC50 = 5.2 nM for wild-type c-Met). It also inhibits VEGF receptor 2 (VEGFR2, IC50 = 112 nM).Formal Name: 7-methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]-quinoline. CAS Number: 1002304-34-8. Molecular Formula: C22H17N5O2. Formula Weight: 383.4. Purity:...
Keywords: 7-methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]-quinoline
Application: Potent c-Met inhibitor, VEGFR2 inhibitor
CAS 1002304-34-8
MW: 383.4 D
From 85.00€ *
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AMG-208
AMG-208

Item number: LKT-A4924.1

AMG-208 is an inhibitor of c-MET and Ron that exhibits anticancer chemotherapeutic activity in prostate cancer models in vitro and in vivo.
Keywords: AMG208
Application: c-MET / Ron inhibitor
CAS 1002304-34-8
MW: 383.4 D
From 144.00€ *
Review
AMG-208
AMG-208

Item number: TGM-T6260-100mg

Description: AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1. Target: c-Met/HGFR, Cytochromes P450. Smiles: COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccccc3)ccnc2c1. References: Liu X, et al. Trends Mol Med. 2010,16(1), 37-45.
Keywords: AMG 208
Application: Potent c-Met inhibitor, VEGFR2 inhibitor
CAS 1002304-34-8
MW: 383.4 D
From 32.00€ *
Review