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SRT 1720 (hydrochloride)
Item number: Cay10011020-1
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
| Keywords: | CAY10559, SIRT 1933, N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide, hydrochloride |
| Application: | SIRT1 activator |
| CAS | 1001645-58-4 |
| MW: | 469.6 D |
From 58.00€
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SRT1720 hydrochloride
Item number: LKT-S7868.1
SRT1720 is an inhibitor of sirtuin 3 (SIRT3) and activator of sirtuin 1 (SIRT1), sirtuins are considered class III histone deacetylases (HDACs). SRT1720 exhibits nephroprotective, anti-aging, anti-inflammatory, and pro-angiogenic activities. SRT1720 binds the acetyl-Lys site on sirtuins rather than the NAD+ site. In...
| Keywords: | STR-1720 HCl salt |
| Application: | SIRT3 inhibitor, SIRT1 activator |
| CAS | 1001645-58-4 |
| MW: | 506.02 D |
From 109.00€
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SRT1720 hydrochloride
Item number: TGM-T2412-100mg
Description: SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5: 0.16 µM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s: 37 µM/300 µM). Target: Sirtuin. Smiles: Cl.O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cnc2ccccc2n1. References: Milne JC et al. Small molecule activators of SIRT1...
| Keywords: | SRT1720 HCl, SRT 1720 Hydrochloride |
| CAS | 1001645-58-4 |
| MW: | 506.22 D |
From 59.00€
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