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BV6
Item number: TGM-T6428-100mg
Description: BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. Target: IAP. Smiles: CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)NCCCCCCNC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C1CCCCC1)C(c1ccccc1)c1ccccc1....
| Application: | IAP inhibitor, bivalent Smac mimetic |
| CAS | 1001600-56-1 |
| MW: | 1205.57 D |
From 45.00€
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BV6
Item number: Cay28830-5
BV6 is a bivalent Smac mimetic and an antagonist of the inhibitor of apoptosis (IAP) proteins that binds to IAP1 and XIAP (Kds = 0.46 and 1.3 nM, respectively). It induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells when used at a concentration of 5 µM. BV6 (4 µM) induces...
| Keywords: | 4,4'-(1,6-hexanediyl)bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolyl-beta-phenyl-L-phenylalaninamide |
| Application: | IAP inhibitor, bivalent Smac mimetic |
| CAS | 1001600-56-1 |
| MW: | 1205.6 D |
From 61.00€
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