3 products were found matching "1001350-96-4"!
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BMS 754807
Item number: Cay17505-1
BMS 754807 is a reversible, orally bioavailable dual inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases (IC50s = 1.8 and 1.7 nM, respectively). It has minimal effect against an array of other tyrosine and serine/threonine kinases. BMS 754807 inhibits cell...
| Keywords: | 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-(2S)-2-pyr... |
| Application: | IGF-1R / InsR inhibitor |
| CAS | 1001350-96-4 |
| MW: | 461.5 D |
From 67.00€
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BMS-754807
Item number: LKT-B5072.1
BMS-754807 is an inhibitor of the insulin receptor (InsR) and IGF-1R that exhibits anticancer chemotherapeutic activity. BMS-754807 enhances the efficacy of other co-administered chemotherapeutics, decreasing levels of activated Akt, increasing cleavage of PARP and caspase 3, and inhibiting proliferation in...
| Keywords: | BMS754807 |
| Application: | InsR / IGF-1R inhibitor |
| CAS | 1001350-96-4 |
| MW: | 461.51 D |
From 94.00€
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BMS-754807
Item number: TGM-T2349-100mg
Description: Dual IGF-1R/InsR Inhibitor BMS-754807 is an oral small molecule inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases with potential antineoplastic activity. Target: Trk receptor, IGF-1R, c-Met/HGFR. Smiles:...
| CAS | 1001350-96-4 |
| MW: | 461.49 D |
From 43.00€
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