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TAK-875
Item number: Cay17335-1
The free fatty acid receptor 1 (FFAR1, GPR40) is highly expressed in pancreatic beta-cells and activated by medium and long-chain fatty acids. There is evidence of a link between FFAR1 (GPR40) and the ability of fatty acids to amplify glucose-stimulated insulin secretion, making this signaling pathway a potential...
| Keywords: | (3S)-6-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid |
| Application: | FFAR1/GPR40 agonist |
| CAS | 1000413-72-8 |
| MW: | 524.6 D |
From 61.00€
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Fasiglifam
Item number: TGM-T2351-100mg
Description: Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist. Target: GPR. Smiles: Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc3[C@H](CC(O)=O)COc3c2)c1. References: Tsujihata Y,et al. TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist,...
| Keywords: | TAK875 |
| CAS | 1000413-72-8 |
| MW: | 524.63 D |
From 45.00€
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