87 products were found matching "916,"!

Description: L 583916 is a bioactive chemical. L 583916 does not inhibit leukotriene synthesis. Target: Others. Smiles: O=C(O)C(C=1C=2C=C(OC)C=CC2N(C(=O)C3=CC=C(Cl)C=C3)C1C)C. References: Kargman S, Vickers PJ, Evans JF. A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells. J Cell Biol. 1992...

Description: VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase. Target: HCV Protease. Smiles: O=C(C1=C(N([C@H]2CC[C@H](OC)CC2)C([C@H]3CC[C@H](C)CC3)=O)C=C(C4=CCCCC4)S1)O[K]. References: Abdelrahman S. Mayhoub. Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure-activity and...

Description: APD-916, an H3 receptor antagonist, exhibits favorable pharmacokinetic properties. Oral administration of APD-916 has been demonstrated to enhance wakefulness in various animal models. Target: Histamine Receptor. Smiles: S(CCCOC)(=O)(=O)C1=CC=C(C=C1)C2=CC=C(CCN3[C@H](C)CCC3)C=C2

Description: NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits...

Human Sperm Proteins Associated with the Nucleus on X-chromosome (SPANX) are relatively low molecular weight cytoplasmic proteins found in testis and sperm. Their expression in other tissues indicates malignancies.

Human TET2, also known as Ten-eleven translocation 2 protein, and methylcytosine dioxygenase TET2, GenBank Accession #NM_001127208, a.a. 916-2002(end) with N-terminal FLAG-tag and C-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW = 126 kDa.

Description: Bocunebart is a humanized monoclonal antibody targeting human adenylate cyclase activating polypeptide (ADCYAP1). It exhibits anti-inflammatory activity by specifically binding to ADCYAP1 and inhibiting associated inflammatory signaling pathways, making it a promising candidate for research in...

Protein function: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). The TRiC complex plays...

Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....